What happens to our immune cells when we get Auto immune disease?


Auto immune disease happens when the body’s natural defense system cannot tell the difference between our own cells and foreign cells, causing the body to mistakenly attack normal cells: immune tolerance disorder.

There are more than 80 types of autoimmune disease, commonly rheumatoid arthritis, Systemic lupus erythematosus, psoriasis, Type I diabetes, etc.

The causes of immune system disorders are not yet completely clear, but it has become clear that regulatory T cells (Treg) are involved.  T cells are one kind of white blood cell.

Regulatory T cells are essential for maintaining peripheral tolerance, preventing autoimmune disease.  But all of the functions of T regulatory cells are not yet clear, so it’s difficult to find the relationship between autoimmune disease and T regulatory cells.

Please see more information about function of regulatory T cells.

 T Cells | Definition, Types & Function - Video & Lesson Transcript | Study.com

→You Tube: “Roles of Regulatory T cells immunology, Immune system, Basic Science Series”



Do you know about white blood cells and what they do?

If you have had a blood test recently and still have the results, please take a look.

White blood cells are immune system cells.

They protect our body from infection or cancer.

They circulate in our blood and respond to injury or illness.

White blood cell formation occurs in our bone marrow: granulocytes, lymphocytes and Monocytes.

  1. “Granulocytes” has 3 types.

Eosinophils, basophils and neutrophils.

  1. “Lymphocytes” grow in the thymus gland, lymph nodes and spleen.

B-cell, T-cell (helper T cell, killer T cell and regulatory T cell), and Natural killer cell

  1. “Monocytes”


For more information about the function of white blood cells, please see

→ https://www.sciencefacts.net/types-of-white-blood-cells.html

 Finally, the relationship between the immune system and the autonomic nerves system is clear.  During the daytime, immune cells stay in the lymph node because sympathetic nerves are active. On the other hand, during the night time, immune cells come out of the lymph nodes and circulate in the blood, looking for foreign bodies.

Therefore, it is very important to stay in harmony with your body clock and get enough sleep at the correct times.

 Thank you!  (Hiroko, Jan.2024)

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